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IVF Laboratory Workshop

Quality Revisited by Accreditation

The IVF Laboratory Day program is especially tailored for embryologists and biologists and will cover various aspects of critical culture conditions, avoiding mistakes, QA, qualifications and competence of personnel. The sessions will include heated debates on types of media, timing of transfer and time lapse and there will be plenty of time for the audience to ask questions.

Course Directors: 
Nelly Achour Frydman, France
Rachel Levy, France
 
Friday, December 5, 2014
 
 8:30 - 10:00
RISK MANAGEMENT IN IVF LABORATORIES
Capsule
Accreditation of IVF laboratories in France has to be achieved according to ISO15189 before 2020. The percentage of accredited laboratories is still low and embryologists have an important task to respond to this legal issue. This session will focus on risk management, personal training, internal control of quality and metrology.
Chairpersons
Nelly Achour Frydman, France
Rachel Levy, France
 
Five basic tools of quality: Material, manpower, method, environment, measurement.
Nelly Achour Frydman, France
 
Metrology: Control CO2 rate and temperature to improve culture conditions
Catherine Patrat, France
 
Personal qualification and competency
Vanina de Larouziere, France
 
Internal quality management: Inter and intra observes variability in embryo quality assessment
Nelly Achour Frydman, France
     
Discussion

  

 10:20 - 11:50
LABORATORY MISTAKES AND PATIENT SAFETY
 Capsule
This session is designed for embryologists and physicians who would like to exchange ideas on all aspects of patients safety. Because of a growing need for good quality and safety in medical care, it is necessary for embryologists and clinicians to improve quality and to be disclosed to patients. In this session we will discuss quality indicators and how to avoid mistakes in ART routine practice. 
 Chairpersons
Nelly Achour Frydman, France
Moncef Benkhalifa, France
 
Are there robust indicators targeting specific steps of ART?
Roger Leandri, France
 
How to avoid laboratory mistakes?
Rachel Levy, France
 
France organization: AMP vigilance
Gaelle Lemardeley, France

  

 12:10 - 13:40
IMPROVING EMBRYO QUALITY AND SELECTION
Capsule
Once suboptimal culture conditions have been optimized and fixed, how to select the best developing embryo?
Do we have new evidence for embryo time-lapse selection: Myth or reality?  
How to improve embryo development without changing culture medium: Grouped embryos or solely: Evidence or intuition?
Chairperson
Rita Vassena, Spain
Nelly Achour Frydman, France
Rachel Levy, France 
 
Debate: Embryos grouping to improve development
Pro: Rachel Levy, France
Con: Jacques Cohen, USA
Discussion
   
Sperm DNA damage: New Strategies of intervention based on indired antioxidants
Maurizio Dattilo, Switzerland

  

 14:30 - 15:30
INDUSTRY SYMPOSIUM

  

 15:30 - 16:00
CONTROVERSIES IN IVF LABORATORY PRACTICE I
Capsule
Accreditation in sperm analysis is also mandatory. The choice of the validation method is crucial, but still debated. How to provide robust sperm indicators?
Chairpersons
Jacques Cohen, France
Nelly Achour Frydman, France
Rachel Levy, France
  
Debate: Sperm kinetics analysis
Sperm morphology: David classification
Florence Eustache, France
Vs.
Kruger classification: Clement Jimenez, France
CASA: Thomas Freour, France
Discussion

   

 16:30 - 17:00
METHOD VALIDATION
Capsule
Acquisition of accreditation is not a final goal but a starting point. An important item is how to validate relevant timing of zygotes and embryos observation using time lapse or static observation. On the other hand, embryos obtained in IVF laboratories are often discarded for their poor morphological feature and their low potential of implantation. Is it ethically acceptable?
Chairpersons
Nelly Achour Frydman, France
Rachel Levy, France
 
How to validate timing of zygotes and embryo observation?
Patricia Fauque, France
 
At which stage do embryo have to be discarded to avoid embryo wasting?
Marine Poulain, France

  

 17:00 - 18:00
CONTROVERSIES IN IVF LABORATORIES PRACTICE II
Organized By Blefco, French Society of Embryology
Capsule
Once optimal culture conditions have been acquired, how to modify them without impacting results? Which policy for an ART center nowadays: Early cleaved embryos or blastocysts? What are the benefits and risks for prolonged embryo culture?  Which are the best culture conditions?
   
How to introduce a new culture media in IVF Lab regarding standard EN ISO15 189?
Charlene Herbemont, France
 
Debate: Culture to blastocyst stage
 Is it valid to observe cleaved embryos?
Yes: Christophe Sifer, France
Do we go directly to blastocyst without cleaved embryo examination?
Nino Guy Cassuto, Isabelle Koscinski, France
Discussion